napqi and glutathione Alcohol paracetamol are both processed through the liver. Paracetamol can form a toxic metabolite called NAPQI, which the body usually neutralises safely. But factors like heavy alcohol use, repeated dosing, fasting Interaction with Ethanol – Alcohol

Interaction with Ethanol Alcohol Metabolism File:Acetaminophen metabolism.jpg Wikimedia Commons A) The CID pathways of N acetyl p benzoquinone imine glutathione Download Scientific Diagram Acetaminophen metabolism. NAPQI, N acetyl p benzoquinone imine; CYP450, Download Scientific Diagram 5 Antidote: NAC (N acetylcysteine) NAC replenishes glutathione, restoring the ability to detoxify NAPQI. It's lifesaving if given early. Example: Hospitals use NAC as the standard treatment for APAP overdose. NAPQI Alchetron, The Free Social Encyclopedia

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