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The unsolved problem of otitis media in indigenous populations: a systematic review of upper respiratory and middle ear microbiology in indigenous children with otitis media

Morphine has a high intrinsic hepatic clearance and about 60% of morphine is removed by first pass extraction after an oral dose

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Autophagy is an evolutionarily conserved catabolic pathway whereby cells, in response to stimuli such as nutrient deficiency, oxidative stress, or pathogen infection, encapsulate damaged or excess organelles and proteins and degrade them through fusion with lysosomes to obtain energy and raw materials