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10.1007/s40618-015-0337-0 57

Toxins now are well established to impair the ability of our mitochondria, the batteries in every cell, to create energy

[3]Current Patent Assignee: JOHNSON JOHNSON CHINA INVESTMENT - WO2019/1420, 2019, A1 Location in patent: Page/Page column 102

This action of CHAC1 aligns with its regulation by transcription factors ATF4 and ATF3, suggesting a tightly controlled mechanism whereby CHAC1 contributes to the cellular apoptosis process, particularly in stress responses ( 4.5 Ferroptosis Ferroptosis is a regulated form of cell death characterized by the accumulation of lipid peroxides, particularly in membrane phospholipids, which occurs when the cellular antioxidant defense is insufficient