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Description

Symptoms of Vitamin B12 deficiency anaemia include sore mouth and tongue, numbness and tingling in the arms and legs, memory loss and depression

Mechanistically, we found that NRF2 is required for the deposition of H3K27ac marks at sites of nascent transcription, including eRNAs

The sirtuin family of NAD+-dependent deacetylases has received particular attention in longevity research

Statistical analysis All quantitative data were subjected to one-way analysis of variance (ANOVA) followed by Bonferronis post hoc comparisons between groups and plotted in the GraphPad Prism 5 sofware package