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Routing of glucose-6-phosphate toward the pentose phosphate pathway is of bilateral importance for cancer: through the oxidative phase, the pentose phosphate pathway will yield NADPH for fatty acid synthesis, cholesterol synthesis, and the detoxification of reactive oxygen species

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Mice in the NC group were fed standard feed, while mice in the OC group and mice in the Lira group were fed HF feed

A second IV of lipoic acid is given to reactivate inactive glutathione