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Previous studies have suggested that PINK1-dependent mitophagy and chemotherapy-induced transcriptional reprogramming may contribute to acquired resistance after NAC, as exemplified by the association of high PINK1 expression in PostNAC specimens with poor prognosis and by organoid-based analyses showing increased tumorigenicity and EMT/hypoxia-related programs after NAC [10, 11]

Additional Information How to cite this article : Zhou, Q

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A Lagoa Pomacanchi cercada por abundantes gramneas naturais, incluindo plantas medicinais, juncos de totora, mirmi e outras espcies, alm de peixes: truta, peixe-rei, huitas, ccarachis, chiis e carpas