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The pharmacokinetics and short-term metabolic effects of a near physiological intravenous GH bolus (200 micrograms) were compared in a group of young (30 yr) and older (50 yr) healthy adults (39)

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Though useful for accounting for study endpoint events in a rapidly fatal disease (i.e., death versus study completion versus trial withdrawal), combined outcomes suffer from issues with cross-trial validity and weighting the importance of relative contributions to outcome (death versus disease progression versus loss of follow-up) in creating the summed rank model [51]

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Redox modulation of the NMDA receptor