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Polygenic risk score identifies subgroup with higher burden of atherosclerosis and greater relative benefit from statin therapy in the primary prevention setting

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In consideration of achieving gender balance across various animal models to ensure the universality of targeting and efficacy, we adopted male APP/PS1 mice for the AD model and female mice for the brain tumor and meningitis models to comprehensively evaluate the VIP system

Anal Bioanal Chem 401:21652175

4 Pectin and diabetes All forms of diabetes are characterized by high blood sugar levels (hyperglycemia), a limited or absent response to insulin, insulin resistance that is specific to certain pathways, and the development of diabetes-related complications in the retina, renal glomerulus, and peripheral nerves [96]

JAK/STAT of all trades: linking inflammation with cancer development, tumor progression and therapy resistance