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doi:10.1016/j.plefa.2005.10.001 Bruton A, Nauman J, Hanes D, Gard M, Senders A

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This blockage of the blood and lymph vessels is what causes the physical manifestations of inflammation, namely redness, pain, stiffness and lack of mobility, and swelling

Moreover, depleting senescent retinal cells has been shown to protect the RGCs in experimental glaucoma 18

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These inflammatory factors, in turn, can further stimulate the secretion of TNF-, forming an inflammatory cascade amplification effect