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J Magn Reson Imaging JMRI

doi: 10.1016/j.bbrc.2004.10.009 23 YePMimuraJOkadaTSatoHLiuTMaruyamaAet al

K.NedergaardM.PreussA.GelbardA

Ho, P.I

Occasional injection site irritation or digestive changes may occur early in use

However, one patient (open squares) dosed with 0.4 mg/kg pegadricase developed only a low titer of 1:120 and was able to maintain serum enzyme activity and low sUA levels for at least 30 days after a single dose (Fig