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Dose adjustment: May be adjusted weekly based on platelet response (target: 50,000/L but 400,000/L)

2014;93(11 Suppl 3):S122-131

Here is what each group received: 1mg group: 1mg weekly for the full 48 weeks, no escalation 4mg (starting at 2mg): Started at 2mg, escalated to 4mg after 4 weeks 4mg (starting at 4mg): Started directly at 4mg, no escalation 8mg (starting at 2mg): Started at 2mg, escalated through 4mg to reach 8mg 8mg (starting at 4mg): Started at 4mg, escalated to 8mg after 4 weeks 12mg (starting at 2mg): Started at 2mg, escalated through 4mg, 8mg to reach 12mg The weight loss results at 48 weeks told a clear story

B12 testing involves measuring serum B12 levels, though methylmalonic acid and homocysteine tests provide more accurate assessments of functional B12 status

Wangchuks fast was broken in the presence of Indian Health Minister JP Nadda and the junior Atomic Energy Minister Jitendra Singh, who offered Wangchuk his first sip to end the protest

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