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The study involved 46 participants who were divided into groups receiving oral placebo, oral glutathione, topical placebo, and topical glutathione

Hereditary hemolytic anemia, characterized by reduced GSH content, has been reported in patients with deficiencies of both GCS and GS activity

As B12 deficiency results in the accumulation of these compounds, levels will appear elevated

LOXs also activate immune cells through LOX-derived proinflammatory metabolites, including leukotriene B4 (LTB4), LTC4, LTD4, LTE4 and Hydroxyeicosatetraenoic acids (HETEs)[110], which indirectly lead to ferroptosis

Two-tailed, one-way ANOVA test was used for biological replicates

Timing strategy: Stick to moderate doses of both