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With age, WAT/body weight ratios increased in WT mice (0.8 +/- 0.1% young, 4.1 +/- 0.3% old) and Has1,3 dko mice (0.8 +/- 0.01% young, 2.3 +/- 0.2% old) but this increase was 44% less in old Has1,3 dko mice

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Found an impurity in blood albumin that suppressed fibrinogen synthesis