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Grady C, Bedarida G, Sinaii N et al

To evaluate the absorption, distribution, metabolism, excretion, and toxicity (ADMET) properties of new molecular entities (NMEs) as early as possible, various in vitro and in vivo methods including medium- and high-throughput screening have been developed, which also facilitate the rapid accumulation of experimental data

Effects of atorvastatin on porcine aqueous humour outflow and trabecular meshwork cells

In dogs with MDR1 mutations, which have defects in transporter operations, the central nervous system becomes more penetrated and has a greater risk of neurotoxicity after an oral dose (87)

The potential gut microbiota-mediated treatment options for liver cancer

FEMS Microbiol Rev 31:293310