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Over five years, the panel held 50 meetings, heard from scores of witnesses, and scoured thousands of pages of research much of it submitted by drug makers themselves

With improvement in knowledge and technology, the term deep clinical phenotyping is increasingly gaining significance

10.1038/s41413-021-00163-z 49 GanY.LiS.LiP.XuY.WangL.ZhaoC.et al (2016)

[PubMed Citation] Curry SC, Connor DA, Raschke RA

ROS signaling by NOX4 drives fibroblast-to-myofibroblast differentiation in the diseased prostatic stroma

Finally, there is no evidence in humans that exogenous lipoic acid can be 'activated' with ATP or GTP and incorporated into lipoic acid-dependent enzymes by a lipoyl transferase (14)