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One plate was analyzed on a large particle flow cytometer (LPFC) with a 405 nm excitation laser, while the other was excited at 488 nm

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On the other hand, C10 affects the paracellular permeability but requires calcium-free buffers, as it precipitates with calcium, an essential ion for tight junction maintenance and physiological relevance (34, 42, 43)

Additionally, the gastrointestinal (GI) absorption efficiencies and bloodbrain barrier (BBB) penetration capabilities were evaluated using the BOILED-Egg classification model, which categorizes the compounds according to their predicted passive absorption and central nervous system access based on the apparent polarity (TPSA) and lipophilicity (WLOGP) values ( Results ChE inhibitory effects of the phenolic compounds As shown in Table 1, all compounds from various chemical groups were tested against 10 mM of the ChEs, of which 12 compounds were able to inhibit AChE, while 8 compounds achieved BChE inhibition over 50%

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Targeting the leukemia microenvironment