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On the contrary, Bacteroides , Parabacteroides , FP , Clostridium leptum , and Prevotella were significantly decreased, and there was a 50% reduction in the high butyrate producer FP (205)

National Sleep Foundation, Sato-Mito, N., Shibata, S., Sasaki, S., & Sato, K

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Phase IIb and Phase III trials showed it did not meet primary endpoints for weight loss versus placebo

It also leads to increased acid production in your stomach, making you more vulnerable to heartburn