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Curcumin exerts context-specific autophagy regulation through dual mechanisms: At moderate concentrations (2025 M), it promotes cytoprotective autophagy via inhibition of the mechanistic target of rapamycin (mTOR)-AKT axis (Zhao et al., 2016), evidenced by decreased p-AKT, p-mTOR, and p-P70S6K expression, coupled with increased microtubule-associated protein 1A/1B-light chain 3- II/microtubule-associated protein 1A/1B-light chain 3-I (LC3-II/LC3-I) conversion

Also, BPC 157 counteracts chronic heart failure (Lovric Bencic et al., 2004) or venous occlusion (Vukojevic et al., 2018)induced hypotension (Lovric Bencic et al., 2004

The role of angiogenesis regarding to the growth of primary tumors along with their metastasis to remote organs is well established (Thaloor et al., 1998)

In patients with PF, the progression of fibrosis is believed to be influenced by three primary factors: excessive epithelial damage caused by inhaled pollutants, senescence, and genetic susceptibility [32]

Skin naturally regenerates and melanin levels can fluctuate over time

Guerquin, M