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doi:10.1093/gerona/glp194 Luo M, Fernandez-Estivariz C, Jones DP, Accardi CR, Alteheld B, Bazargan N, Hao L, Griffith DP, Blumberg JB, Galloway JR, Ziegler TR (2008) Depletion of plasma antioxidants in surgical intensive care unit patients requiring parenteral feeding: effects of parenteral nutrition with or without alanyl-glutamine dipeptide supplementation

Knockdown experiments have further confirmed the critical role of the Nrf2 pathway in this process

In view of the aforementioned findings, GPX7 is abundantly expressed in aggressive gliomas, suggesting that GPX7 might be involved in the malignant progression of gliomas

This dual-enzyme cascade is widely present in the cytoplasm and is highly sensitive to oxidative stress

Effects vary depending on individual hydration, nutrition and lifestyle

This detoxification process primarily occurs in the liver, where GSH binds to foreign compounds