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During cancer development and metastasis, tumor cells acquire enhanced invasiveness and migratory capabilities through EMT ( Tumor cells with high ZEB1 expression exhibit heightened dependence on GPX4, as GPX4 counteracts the oxidative effects of intracellular peroxides on PUFAs in cellular membranes, thereby attenuating ferroptosis

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Exogenous insulin-like growth factor 1 enhances thymopoiesis predominantly through thymic epithelial cell expansion

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