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Meshchaninov VN, Tkachenko EL, Zharkov SV, Gavrilov IV, Katyreva IuE

The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

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Functional dissection using chimeras revealed that swapping the full HFD of Taf12 with that of Taf12L (Taf12C5) resulted in partial rescue of the growth phenotype (Figure 6) , similar to that observed with full-length Taf12L suggesting that sequences outside the HFD play a minimal role in Taf12-specific function and complex association