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Detecting heteroplasmy from high-throughput sequencing of complete human mitochondrial DNA genomes

It also interfaces with intracellular signaling networks connected to oxidative balance and cellular stress-response mechanisms

10.1007/s13205-024-04204-2 70 LvT.FanX.HeC.ZhuS.XiongX.YanW.et al (2024)

Keywords: reactive oxygen species, oxidative stress, antioxidant defenses, superoxide dismutase, therapeutic potential 1

The authors found that a 12-hour protocol of IV NAC had fewer adverse effects than a 20-hour protocol, although there was insufficient power to determine if the shorter duration had similar efficacy