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At physiological pH, H 2 S (pKa ~7) exists predominantly (~70%) as the hydrosulfide anion (HS ) while the conjugate acid freely diffuses through biological membranes to access the catabolic machinery within mitochondria 4

Or, perhaps more optimistically, could they work together

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Conclusion: We observed independent associations between baseline TNF-alpha and recurrent vascular events after stroke

These results were observed under controlled laboratory conditions and should be interpreted with caution

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