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These receptors are activated endogenously by bile acids and are regulators of bile acid production, conjugation, and transport

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This leads to changes in astrocytic glucose metabolism and glutamate transport, which in turn influence neuronal function by altering synaptic transmission and energy supply

[9] Many of the systemic diseases cause other symptoms apart from oral ulceration, which is in contrast to aphthous stomatitis, where there is isolated oral ulceration

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Sci Rep 15 , 30568 (2025)