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A time step of 1.0 fs and a total time of a simulation run of up to 10 ps were used to equilibrate the system at the DFT level

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Macro- ATG consists in the delivery of cytoplasmic cargo to the lysosome through the intermediary of a double membrane bound vesicle, the autophagosome, which fuses with the lysosome to form an autolysosome (Zhang, 2013)

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