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Analysis using proteomics Proteomics, the comprehensive analysis of the entire protein complement within a biological sample, such as blood cells or plasma, offers valuable insight into disease-specific biomarkers (Coorssen, 2022)

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For functional impairment, the Oswestry Disability Index (ODI) was used in three studies [60,61,65], and the RolandMorris Disability Questionnaire (RMDQ) was used in one study [64]

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