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Furthermore, measurement of intracellular ROS levels revealed that supplementation of formononetin led to elevated levels of ROS in SREBP1-RNAi MDA-MB-231 cells, whereas co-administration of Trion-1 did not mitigate ROS levels (Figure 5D)

Pharmacology & Toxicology, 88, 8188

Klnemann M, Andrejev S, Blasche S, Mateus A, Phapale P, Devendran S, Vappiani J, Simon B, Scott TA, Kafkia E et al (2021) Bioaccumulation of therapeutic drugs by human gut bacteria