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Some people may combine forms depending on goals, but total dosage, tolerance, and personal needs should be considered to avoid unnecessary supplementation

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It was suggested that PGE 1 confers protection against endometriosis by attenuating the secretion of TNF-, IFN- and interleukins (IL-2, IL-4 and IL-6), while PGE 2 induces cytokine release and thus endometriosis through its apoptotic and inflammatory functions [19, 46]