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Candidate bioactive species can be introduced into ML cell lines and one can screen for bioactive species which alter the intracellular processing of foreign bioactive species and sequence of the foreign peptide that is presented to T cells by MLs on their cell surface in the context of Class II MHC

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The complication is that low B12 in cats is often linked to absorption problems from gastrointestinal disease, meaning adequate intake may still not translate into adequate blood levels

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