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This process was repeated, and the solution was concentrated to 1000 mL, lyophilized to yield 27.4 g of powder, and stored at -20C

(Bateman et al., 29423816) N-acetylcysteine can be used in patients with a history of anaphylactoid reactions (although it may be wise to initiate the infusion at a lower dose and pre-treat with antihistamines)