chac1 glutathione Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis journal club - Kidney International

journal club Kidney International Frontiers CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC Nature Communications Glutathione (GSH) depletion by ChaC1 results in a more oxidizing Download Scientific Diagram Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv Long noncoding RNA GDIL acts as a scaffold for CHAC1 and XRN2 to promote platinum resistance of colorectal cancer through inhibition of glutathione degradation Cell Death & Disease

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