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Increased production of pro-inflammatory cytokines by macrophages and an increase in pro-inflammatory adipokines like leptin and resistin are two ways in which obesity impacts adipocytes (Wong et al

Consistent with the result that Ser184 phosphorylation was essential for GSTP to enter nucleus, both immunoblotting and confocal microscopy detection demonstrated that GF109203X inhibited LPS-triggered GSTP nucleus translocation, and PMA promoted GSTP to enter the nucleus in LPS-untreated RAW264.7 cells (Figures 6F,G)

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