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Taken together, these results indicate that proline could promote tumour growth by inhibiting the level of uridine in vivo

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Yak1p activity appeared to be mediated by its kinase activity as its effect was lost when a kinase dead (KD) form p.K398R of YAK1 (Moriya et al., 2001) was used (Figure 1D)

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Because the transsulfuration pathway consumes SAM without replenishing methionine, its hyperactivity leads to reduced SAM availability (29)

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The findings are clear: problems occur when we are overwhelmed with too much oxidative stress or too many toxins

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Serum Vitamin Levels and Their Relationships with Other Biomarkers in Korean Breast Cancer Patients

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Day N, Oakes S, Luben R, Khaw KT, Bingham S, Welch A, Wareham N

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