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A Phase 2 study published in The New England Journal of Medicine (Jastreboff et al., 2023) reported substantial weight reduction in participants with obesity

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More research is needed to determine whether garlic supplements are safe for people on anticoagulatory therapy

Therefore, parenteral cyanocobalamin should be administered to a pregnant woman if the benefits outweigh the risks.[15][16] Cyanocobalamin is excreted in the breast milk of nursing women in levels similar to the level of vitamin B12 in maternal plasma.[25] The distributed cyanocobalamin in breast milk has been found to be compatible with breastfeeding by the American Academy of Pediatrics.[26] In addition, there has not been any reports of adverse effects associated with the intake of normal daily requirements of vitamin B12 during lactation

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Injections are typically administered by healthcare professionals and may be given as a series of doses initially, followed by maintenance injections at intervals determined by individual needs