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Female WT C57BL/6 mice, 610 weeks old, were purchased from Center for Laboratory Animal Facilities of the Universidade Federal de Minas Gerais (CEBIO-UFMG)

The mainstay of therapy is intensive behavioral interventiongiven for 20 or more hours per weekwhich has been shown to produce important benefits, but response to treatment varies widely, and it is challenging to predict which children will respond [5]