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Podlesny D, Durdevic M, Paramsothy S, et al

Lack of clinical evidence: Although there is encouraging preclinical research indicating the neuroprotective potential of phytochemicals in TBIs, the absence of comprehensive clinical data hinders the ability to substantiate their effectiveness and safety in human patients

doi: 10.1371/journal.pone.0003952 66 SlavinJ

Serum IgG, IgA, and IgM levels reach a plateau between two and four weeks PSO [68, 71, 72, 76], before IgM and IgA decline to preinfection levels in the majority of patients within three months [68, 77,78,79,80]

These advances collectively broaden the landscape for peptide investigation, moving toward more predictable absorption models and robust experimental reproducibility