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This can be summarized as follows: + Coenzyme A + + This enzyme is part of ethanol fermentation in certain species, and in particular the conversion of pyruvate to ethanol

Both technologies can be used for analyzing short strands of bisulfite-treated DNA just as the old techniques, but the main advantage is that bisulfite treatment is no longer required for sequencing DNA, as ONT and SMRT can detect many types of DNA modifications simultaneously on long strands, allowing genome, epigenome, transcriptome and epitranscriptome profiling without specific prior sample preparation [25,26,27]