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It is important to be aware of this in the design because 80kPa pressure loss could be the difference between supplying a compliant pressure at the fixture and a non-compliant pressure at the fixture

In most cases, symptoms should improve within 2-4 weeks as tolerance develops

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Keep containers sealed, note lot and preparation details, and store in a cool, dry place protected from direct light

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Timing of administration relative to surgical procedures, optimal dosing in perioperative settings, and integration with standard post-operative care protocols require clinical investigation before establishing evidence-based perioperative protocols