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These findings demonstrate that GSH depletion- and biosynthesis inhibition-induced ferroptosis and pyroptosis strategy would provide insights in designing GSH-exhausted medicines

De Haro Muoz, and Dr

Peer review Peer review information Communications Biology thanks the anonymous reviewers for their contribution to the peer review of this work

Lipid droplets in cancer cells and tumor-associated macrophages contribute to immune evasion, and targeting lipid accumulation could restore anti-tumor immunity

Bulteau AL, Dancis A, Gareil M, Montagne JJ, Camadro JM, Lesuisse E: Oxidative stress and protease dysfunction in the yeast model of Friedreich ataxia