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Only moisture can seep into the deep layer of skin, according to a research of the water content distribution ratio of skin cells and the cuticular layer

A natural polyphenol activates and enhances GPX4 to mitigate amyloid- induced ferroptosis in Alzheimers disease

Received: 13 May 2025 Revised: 04 June 2025 Accepted: 23 June 2025 Published: 27 June 2025 2025 The authors

Preparation and evaluation of chitosan- and hyaluronic acid-grafted pullulan succinate films for skin wound healing

Although the intracellular concentration of GSH in neurons is high 77,78,79 , the CSH content is very low (under the detection limit 77 ) and, therefore, an efficient CSH-dependent GSH oxidation is unlikely in these cells

In addition, haem oxygenase 1 (HMOX1) is upregulated in embryonic ferroptosis, and inhibition of HMOX1 can maintain normal mitochondrial function, thereby preventing ferroptosis from occurring [16]