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10.1212/wnl.57.8.1422 Neurology 58 OhgamiR

Bacterial overgrowth syndrome may cause cobalamin deficiency because of competition for cobalamin in the intestine before the "cobalamin-intrinsic factor" complex reaches the terminal ileum

For some, particularly those with permanent malabsorption issues, injections are a regular, lifelong requirement, typically lasting between two to three months per dose

In a subsequent study, Caddeo et al

The aging process can affect the stomachs ability to produce intrinsic factor, necessary for B12 absorption

In brief, scores above 90 are considered as very accurate for local features and potentially side chains, 7090 as good for overall fold with secondary structure, 50-70 as low confidence including the visual representation, and below 50 as likely disordered until in the right context