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Nitrosative stress in Parkinson's disease

[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Manglik, A

Cancer Facts & Figures 2025

5,023,252 discloses the use of pharmaceutical compositions comprising a neurologically active drug and a compound for facilitating transport of the drug across the blood-brain barrier including a macrocyclic ester, diester, amide, diamide, amidine, diamidine, thioester, dithioester, thioamide, ketone or lactone

It has antibacterial activity against a broad spectrum of Gram negative and Gram positive bacteria

However, much of the discussion and consideration relates to therapeutic agents, in part because generally the Food and Drug Administration (FDA) requires more information on ADME than do other regulatory agencies (e.g., Occupational Safety & Health Administration (OSHA), United States Environmental Protection Agency (USEPA)) before the chemicals they regulate that would result in human exposure to the chemical can be used