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Collectively, these in vitro and in vivo data suggest that in addition to Sororin recruitment, RSMC also stimulates Sororins anti-Wapl activity

Chronic inflammation leads to apoptosis of VAT resident macrophages The balance between monocyte-derived infiltrating and tissue-resident macrophages in metabolic tissues is a key contributing factor in the maintenance of metabolic health

J Biol Chem, 2007

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These factors initiate the recruitment of inflammatory cytokines in the conjunctiva, leading to a delayed ocular response

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