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For the construction of the metE mutant, the AES -which contained a Kan R cassette and the GFP gene optimized for its expression in mycobacteria (eGFP) (Supplementary Note 1)- was synthesized by GenScript

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The US-FDA initially approved the drug in 1942 (7)

This holistic approach ensures long-term resolution of the deficiency

For more information about generic drug approval and bioequivalence, you can visit the FDA website: Dosage: Generic cyanocobalamin is available in different forms and strengths: Vials: 1000 mcg/ml in 10 ml and 30 ml vials Ampoules: 1000 mcg/ml in 1 ml ampoules Your doctor will determine the appropriate dosage based on the individual needs and medical conditions