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Wijeysundera DN, Karkouti K, Rao V et al

Saitakis G., & Chwalisz B

Reduced glutamate uptake 278 and increased release of GABA 279 also affect synaptic transmission and plasticity, arguably contributing to the pathophysiology of depression

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J.ButlerL

The biological roles proposed for GHK-Cu in the research literature have included effects on collagen and extracellular matrix synthesis (through copper-dependent enzymes including lysyl oxidase), on antioxidant gene networks (where copper participates in both prooxidant and antioxidant chemistry depending on context), on growth factor activity in tissue repair, on hair follicle biology, and on broader transcriptional programs characterized in microarray and RNA-seq studies