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Valenstein, M

[6] El glutatin se sintetiza en dos pasos dependientes del trifosfato de adenosina: En primer lugar, la gamma-glutamilcistena se sintetiza a partir del L-glutamato y la cistena a travs de la enzima gamma-glutamilcistena sintetasa (tambin conocida como ligasa glutamato-cistena (GCL) ligasa)

In addition, curcumin acts as DNA hypomethylation agent to restore the expression of Nrf2 via demethylation of promoter CpGs [220]

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Its relatively small size and well-characterised binding chemistry make it a practical tool for investigating copper-mediated biological processes in both in vitro and in vivo models