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[1] As a first-generation ethanolamine antihistamine, the formulation is used when oral therapy is impossible or impractical to manage acute IgE-mediated reactions, adjunctive treatment of anaphylaxis (after epinephrine), prophylaxis of blood-product hypersensitivity, motion sickness that precludes enteral dosing, and selected extrapyramidal syndromes

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Prostaglandins Leukot Essent Fatty Acids 1992

BPC-157s resistance to gastric degradation has led researchers to propose that oral administration may deliver systemic activity, not merely local gut effects

J Appl Phys