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Not automatically in a non-facility setting

Immediate medical attention is necessary if bloating is accompanied by: Severe, persistent, or worsening abdominal pain that does not resolve with position changes or over-the-counter remedies Inability to pass gas or have bowel movements, suggesting possible bowel obstruction Persistent vomiting, particularly if unable to tolerate oral fluids, raising concern for gastroparesis or pancreatitis Signs of dehydration (dizziness, reduced urination, dark urine) Fever, which may indicate infection or inflammation Bloody or black tarry stools Right upper quadrant pain or jaundice (yellowing of skin or eyes), which may suggest gallbladder disease Unintentional rapid weight loss beyond expected therapeutic effects Patients should stop tirzepatide and contact their healthcare provider immediately if they experience severe or persistent abdominal pain, with or without vomiting, as these may be symptoms of acute pancreatitis

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Schwangere oder stillende Frauen sollten ihren Arzt oder ihre rztin konsultieren

362 Primary resistance refers to tumors that exhibit minimal or no response to standard treatments, including chemotherapy, targeted therapy, or immunotherapy, from the start of treatment

As secondary symptoms, many MdDS patients develop anxiety and depression 4,24