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Cystic fibrosis transmembrane conductance regulator channel dysfunction in non-cystic fibrosis bronchiectasis

Cytochrome P450 enzymes cannot oxidize NADPH directly, instead these electrons are relayed via the Fe-S cluster containing protein FDX1 89,95

PMID: 29490099

PLoS ONE 8:e80298

Collectively, these varied biologic actions provide the pathophysiological basis for the signs and symptoms observed in eosinophil-associated diseases