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It is generally avoided in people with iron overload conditions such as hemochromatosis, those with a history of serious reactions to IV iron, and certain active infections and it requires extra caution in pregnancy and some chronic conditions

This nuclear localization in elderly Leydig cells correlated with reduced expression of 3-HSD, a crucial enzyme for testosterone synthesis, suggesting a link between nuclear FOXO4 and age-related decline in testosterone production [2]

Providers should document pain levels, functional limitations, and objective findings like spasm or decreased range of motion

There is a small chance of allergy or irritation, but this is rare with correct use

Our team put together a simple table to break it down

PMID: 6562087 Nath, P., et al